Neurocosmetics – The Science Behind Healthier Skin and a More Youthful Appearance
- Aug 21, 2025
- 3 min read
Alondra Forteza Cedeño is a Biomedical and Medical Esthetician who incorporates the best scientific evidence and technology, offering the best treatments for her patients. She is the founder of Mímate Aesthetic & Spa, a medical spa to improve the health of your skin.
Neurocosmetics is a pioneering field in aesthetic science-medicine that focuses on the communication between the skin and the nervous system to address aesthetic and psychological benefits. Maybe you haven’t noticed, but our skin interacts with the nervous system through sensory nerve endings and endocrine cells. This innovative pathway of neurocosmetics describes this relationship that improves many skin concerns, such as aging, hydration, elasticity, barrier function, and many other benefits through skin neuronal pathways and bioactive compounds.
Nervous system + the skin
As it is true that the skin is our largest organ, the association between the skin and the nervous system is correlated. Recent studies have shown that the use of certain ingredients of skincare and their delivery system can focus on regulating the activity of neurotransmitters and neuroactive compounds.
If you apply skincare to maintain the skin stability, prevent signs of aging, and even treat specific concerns such as pigmentation and acne. This field has proven that specific ingredients with advanced topical penetration methods can interact through these neuronal pathways in the skin tissue and are responsible for producing the desired results.
Anti-aging treatments are one of the most common concerns, and in these cases, focusing on neurocosmetics, it has been shown that neuropeptide-based formulations like acetyl hexapeptide-8 (argireline) reduce the formation of wrinkles, inhibiting the release of neurotransmitters at neuromuscular junctions by blocking the muscle movements. This is one of the many excellent non-injectable options with incredible and natural results that last. So, as a Biomedical, I always state in the clinic that it’s okay if you use injectables as an anti-aging treatment, but specific skincare and non-invasive treatments help improve the results of the injectables or make them last longer. And who does not want to continue improving their cosmetic treatments?
Know your skincare
As mentioned, skincare ingredients with bioactive compounds are capable of interacting at a cellular level depending on your concern, not only promoting a healthier skin or helping maintain control of melasma, acne, rosacea, etc. It also promotes the clinical efficacy of the clinic’s professional treatments to provide incredible benefits. Ingredients like peptides, niacinamide, and plant extracts can also “modulate” stress pathways, reduce skin inflammation, and enhance the skin barrier function.
Also, our skin is composed of sensory neurons, which not only transmit sensory information but also can release neuropeptides and neurotransmitters that produce skin reactions. So yes, when you apply a product that smells great, that can create neurological responses in your brain and in your skin, reducing even cortisol or stress levels.
The power of skincare ingredients
This pioneering field of neurocosmetics not only evidences the power of specific formulations and skincare products it also confirms that what you apply on your skin passes through different processes that we don’t see but are potential. This is why skincare and in-clinic treatments are always the best combination to promote the best results, depending on your skin needs.
Get your best results
In our clinic, we focus on offering non-invasive treatments with long-lasting results with these science-evidenced formulations, that last and promote natural looks, preventing surgeries or even injectables with excellent results. We are here to help you use the best skincare ingredients for the necessities of your skin. Search our social media to create your virtual consult.
Read more from Alondra Forteza Cedeño
Alondra Forteza Cedeño, Biomedical, Biomedical Aesthetics
Alondra Forteza Cedeño is a Biomedical and Medical Esthetician who incorporates the best scientific evidence and technology, offering the best treatments for her patients. She is the founder of Mímate Aesthetic & Spa, a medical spa with the mission to improve the health of your skin. She is certified in the most effective skin treatments and innovative technology. Alondra is constantly educated, and she uses her social media to educate and provide valuable information for the benefit of all.
References:
Basit H, Godse KV, Al Aboud AM. Melasma. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available here.
Rostami Mogaddam M, Iranparvar Alamdari M, Maleki N, Safavi Ardabili N, Abedkouhi S. Evaluation of autoimmune thyroid disease in melasma. J Cosmet Dermatol. 2015 Jun;14(2):167-71. doi: 10.1111/jocd.12138. Epub 2015 Mar 23. PMID: 25810215.
RUBÉN J. LUTFI, MIGUEL FRIDMANIS, ALEJANDRO L. MISIUNAS, OSCAR PAFUME, ENRIQUE A. GONZALEZ, JORGE A. VILLEMUR, MIGUEL A. MAZZINI, HUGO NIEPOMNISZCZE, Association of Melasma with Thyroid Autoimmunity and Other Thyroidal Abnormalities and Their Relationship to the Origin of the Melasma, The Journal of Clinical Endocrinology & Metabolism, Volume 61, Issue 1, 1 July 1985, Pages 28–31.
