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The Gut-Skin Axis and Why Healthy Skin Truly Starts From Within

  • Sep 2, 2025
  • 4 min read

Katarina Lijovic is a Functional Nutrition and Holistic Wellness expert who successfully applies her knowledge and skills to help individuals and communities to optimize their health and quality of life.

Executive Contributor Katarina Lijovic

We often think of skin health as something that can be fixed with the right cream or serum. For years, skincare has been marketed as something that happens on the surface, through creams, serums, and treatments. While topical care plays its role, the truth is that your skin reflects your internal health. Science increasingly shows that our skin’s health is deeply connected to what’s happening inside the body, especially in the gut.


Woman smiling in a light gray blazer, standing in a modern room with circular lights on a white wall, and green plants nearby.

This connection, known as the gut-skin axis, refers to the intricate communication between the gut microbiome, the immune system, and the skin. When the gut is in balance, nutrients are well absorbed, inflammation is kept in check, and detoxification flows smoothly, conditions that promote clear, vibrant skin. But when there’s an imbalance, the effects can appear right on the surface.


The gut microbiome: Your skin’s silent partner


The gut is home to trillions of microorganisms, bacteria, fungi, and other microbes that collectively make up the gut microbiome. A balanced microbiome supports healthy digestion, nutrient synthesis, and immune regulation. A healthy, diverse microbiome also supports a calm, resilient skin barrier. When this balance is disrupted (i.e., dysbiosis), it can lead to increased intestinal permeability (“leaky gut”) and systemic inflammation.


Inflammation is a key driver in many skin conditions. This systemic inflammation often shows up as:


  • Acne - often linked to inflammation and imbalanced gut flora.

  • Rosacea - strongly associated with small intestinal bacterial overgrowth (SIBO).

  • Eczema and psoriasis - both can flare when gut inflammation is high.


Emerging research suggests that people with these conditions often have underlying gut imbalances, such as:


  • Dysbiosis - An overgrowth of harmful bacteria or depletion of beneficial bacteria.

  • Small Intestinal Bacterial Overgrowth (SIBO) - Excess bacteria in the small intestine, linked to rosacea and other inflammatory skin issues.

  • Gut-derived inflammation - Immune activation that triggers inflammatory pathways affecting the skin barrier and oil production.


Liver health and skin appearance


The liver plays a central role in detoxifying the body, filtering out toxins, metabolizing hormones, and processing metabolic waste. When the liver’s detoxification pathways are sluggish (due to nutrient deficiencies, high toxic load, alcohol, certain medications, chronic inflammation, or genetic polymorphisms or mutations that impair detoxification pathways), the skin often becomes an “alternative elimination route.”


This can manifest as:


  • Dull or congested skin

  • Increased breakouts

  • Hyperpigmentation

  • Redness or irritation


Supporting liver health through a nutrient-rich diet, adequate hydration, and minimizing toxin exposure helps reduce the burden on the skin.


Nutrient deficiencies that show on skin


Your skin relies on a constant supply of specific nutrients to renew, repair, and protect itself. Deficiencies in these key building blocks can cause visible changes:


  • Omega-3 fatty acids - A lack can lead to dryness, flakiness, and increased inflammation.

  • Collagen & protein - Low intake can cause loss of elasticity, premature wrinkling, and slower healing.

  • Vitamin C - Essential for collagen synthesis; a deficiency may lead to rough texture and slower recovery from blemishes.

  • Zinc - Supports wound healing and reduces inflammation; low levels often worsen acne.

  • B vitamins - Especially B7 (biotin) and B3 (niacin) for barrier function and hydration. Additionally, a deficiency in vitamin B6 can manifest as cracked corners of the mouth, while cracked lips can be due to a vitamin B2 deficiency.


When gut health is compromised, absorption of these nutrients declines – meaning even a nutrient-rich diet may not fully benefit your skin until the gut lining is healed.


Stress and the skin


The gut-skin connection doesn’t stop with food and digestion; stress is another critical factor. When we’re under chronic stress, the body releases cortisol, which not only disrupts the gut microbiome but also increases oil production and inflammation in the skin. Stress can delay wound healing, worsen acne flare-ups, and trigger inflammatory skin conditions.


Mind-body practices such as breathwork, meditation, or even daily walks can lower cortisol levels, protect the gut barrier, and, by extension, improve skin health.


Building skin health


Addressing skin concerns holistically means looking beyond topical solutions and working on the internal systems that keep skin vibrant and resilient. A gut-focused skincare approach may include:


  • Restoring microbiome balance with probiotics, prebiotics, and a whole-food diet.

  • Addressing SIBO or dysbiosis through targeted protocols guided by a qualified practitioner.

  • Supporting liver detox pathways with cruciferous vegetables, antioxidants, and adequate protein.

  • Ensuring nutrient sufficiency in key nutrients for healthy, glowing skin.

  • Managing stress to protect the gut-skin connection.

  • Being happy and content. That also shows as a glow on the skin.


When gut health is restored, inflammation lowers, detox pathways flow smoothly, and nutrient absorption improves, creating the optimal conditions for healthy, glowing skin.


Healthy skin comes from within


The gut and skin are not separate systems working in isolation; they’re deeply interconnected. Your skin is often the first visible signal that something inside needs attention. Whether it’s dysbiosis, SIBO, sluggish liver function, nutrient deficiencies, or unmanaged stress, these internal imbalances eventually manifest externally.


Lasting skin health isn’t just about what you put on your face. It’s about restoring internal balance so your skin can reflect vitality naturally. Nourish your gut, protect your liver, correct nutrient deficiencies, improve lifestyle habits, and manage stress. When the inside thrives, your skin can’t help but show it.


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Read more from Katarina Lijovic

Katarina Lijovic, Functional Nutrition Counselor/Nutritionist

Katarina Lijovic is a Nutritionist and Functional Nutrition Counselor who focuses on addressing the root causes of nutritional imbalances and health concerns, rather than merely managing symptoms. By using a holistic, personalized approach, Katarina works to optimize an individual’s health through tailored nutrition plans, lifestyle modifications, and evidence-based practices. Her mission is to guide individuals toward long-term, sustainable solutions. With her focus on prevention and balance, Katarina empowers individuals to make informed choices that support their overall health and well-being.


This article is published in collaboration with Brainz Magazine’s network of global experts, carefully selected to share real, valuable insights.

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